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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4004 | Concanavalin A | Apoptosis | |
Concanavalin A is a plant lectin that is a T cell mitogen. It induces apoptosis in human fibroblasts. | |||
T14074 | A-770041 | Src | |
A-770041 is a selective and orally active inhibitor targeting the Src-family kinase, Lck, which plays a crucial role in T-cell signaling. With an IC50 value of 147 nM at 1 mM ATP, A-770041 demonstrates high specificity b... | |||
T36696 | DMBA | ||
7,12-Dimethylbenz[a]anthracene (DMBA) is a polycyclic aromatic hydrocarbon (PAH) that has been found in tobacco smoke and diesel exhaust and has carcinogenic activity.1,2It undergoes metabolic activation by numerous enzy... | |||
T68351 | Homodestcardin | ||
Homodestcardin is a cyclic depsipeptide fungal metabolite that has been found in T. roseum and has immunosuppressant activity. It inhibits concanavalin A-induced proliferation of isolated mouse T cells. | |||
TN2224 | Soyasapogenol A | TNF | |
Soyasapogenol A shows estrogenic and hepatoprotective activities, it directly prevents apoptosis of hepatocytes, and secondly, inhibits the elevation of plasma TNF-α±, which consequently resulted in the prevention of liv... | |||
T38038 | (-)-Rasfonin | ||
(-)-Rasfonin is a fungal metabolite that has been found in T. terrophilus.1 It inhibits proliferation of mouse splenocytes induced by concanavalin A and LPS (IC50s = 0.7 and 0.5 μg/ml, respectively). References1. Fujimot... | |||
T37288 | Remisporine B | ||
Remisporine B is a polyketide and derivative of remisporine A that has been found inPenicilliumand has immunosuppressant activity.1,2It inhibits LPS- or concanavalin A-induced proliferation of isolated mouse splenic lymp... | |||
T36986 | Colletodiol | ||
Colletodiol is a fungal metabolite that has been found inD. grovesiiand has immunosuppressant and antiviral activities.1,2It inhibits concanavalin A- or LPS-induced proliferation of isolated mouse splenocytes (IC50s = 12... | |||
T36355 | Sydowinin B | ||
Sydowinin B is a xanthone polyketide that has been found inA. sydowiiand has immunosuppressant activity.1It inhibits LPS- or concanavalin A-induced proliferation of isolated mouse splenic lymphocytes (IC50s = 19.2 and 20... | |||
T35761 | Carviolin | ||
Carviolin is an anthraquinone fungal metabolite that has been found inZ. longicaudatawith immunosuppressive and antitrypanosomal activities.1,2It inhibits LPS- or concanavalin A-induced proliferation of mouse splenocytes... | |||
T35995 | Ferrichrome (iron-free) | ||
Ferrichrome (iron-free) is a hydroxamate siderophore produced by various fungi (including U. sphaerogena) that facilitates iron chelation and uptake by these organisms and is also used by bacteria as a heterologous sider... | |||
TN6539 | Pd-C-II | ||
Pd-C-II has anti-inflammation activity, it can inhibit TNF-α production and iNOS protein expression and inhibit COX-2 protein expression in LPS-stimulated RAW 264.7 cells. Pd-C-II inhibits anaphylactic mediator release f... | |||
T35979 | Benastatin C | ||
Benastatin C is a polyketide synthase-derived benastatin that has been found inStreptomycesand has diverse biological activities.1,2It inhibits glutathione S-transferase (GST; IC50= 24 μg/ml for the rat liver enzyme).2Be... | |||
T83864 | Plipastatin A1 | SNA-60-367-3,Fengycin IX | |
Plipastatin A1, a lipopeptide isolated from B. cereus, demonstrates enzyme inhibitory and immunosuppressant properties. It effectively inhibits enzymes phospholipase A2 (PLA2), phospholipase C (PLC), and phospholipase D ... | |||
T83829 | 2'-Deoxy-1,N6-ethenoadenosine-5'-O-triphosphate sodium | ε-dATP | |
2'-Deoxy-1,N6-ethenoadenosine-5'-O-triphosphate (ε-dATP), a fluorescent derivative of 2’-deoxyadenosine-5’-O-triphosphate (dATP), promotes sister chromatid exchange in stimulated primary mouse spleen T- and B lymphocytes... | |||
T36618 | Rupatadine | ||
Rupatadine (UR-12592) is a potent dual PAF/H1 antagonist with Ki of 0.55/0.1 uM(rabbit platelet membranes/guinea pig cerebellum membranes).IC50 value:Target: PAF/H1 antagonistin vitro: Rupatadine competitively inhibited ... |